NEUROSURGERY Report

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Posts Tagged ‘epilepsy surgery

Ahead of Print: Epilepsy Surgery for Glioneuronal Tumors in Childhood

Background: In contrast to the abundance of seizure outcome reports in epilepsy surgery for glioneuronal tumors in childhood and adolescence, there is a dearth of information regarding cognitive outcomes.

Objective: To investigate the seizure and cognitive outcome of children and adolescents that underwent resective surgery for glioneuronal tumor-associated refractory epilepsy and, determine their predictive factors.

Methods: We retrospectively analyzed the presurgical findings, resection types and outcomes over 1.3-12.3 years (mean 7.3) of 29 consecutive patients, who underwent resection in 2000-2011. The mean age at epilepsy onset was 7.9 years (range 0-15.4), the mean age at surgery was 11.7 years (range 2.6-17.3), and the mean epilepsy duration to surgery was 3.8 years (range 0.3-15.3). Etiology comprised 13 dysembryoplastic neuroepithelial tumors and 16 gangliogliomas, with additional focal cortical dysplasia in 5 cases.

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Written by NEUROSURGERY® Editorial Office

May 9, 2014 at 8:00 AM

Ahead of Print: Safety of Staged Epilepsy Surgery in Children

Background: Surgical resection of epileptic foci relies on accurate localization of the epileptogenic zone, often achieved by subdural and depth electrodes. Our epilepsy center has treated selected children with poorly localized medically refractory epilepsy with a staged surgical protocol, with at least one phase of invasive monitoring for localization and resection of epileptic foci.

Objective: To evaluate the safety of staged surgical treatments for refractory epilepsy among children.

Methods: Data were retrospectively collected, including surgical details and complications of all patients who underwent invasive monitoring.

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Written by NEUROSURGERY® Editorial Office

October 31, 2013 at 8:00 AM

Free Article with CME: Seizure Types after Temporal Lobectomy

Background: Temporal lobectomy can lead to favorable seizure outcomes in medically-refractory temporal lobe epilepsy (TLE). Although most studies focus on seizure freedom after temporal lobectomy, less is known about seizure semiology in patients who “fail” surgery. Morbidity differs between seizure types that impair or spare consciousness. Among TLE patients with seizures after surgery, how does temporal lobectomy influence seizure type and frequency?

Objective: To characterize seizure types and frequencies before and after temporal lobectomy for TLE, including consciousness-sparing or consciousness-impairing seizures.

Methods: We performed a retrospective longitudinal cohort study examining patients undergoing temporal lobectomy for epilepsy at our institution from January 1995 to August 2010.

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Written by NEUROSURGERY® Editorial Office

October 25, 2013 at 8:00 AM

Ahead of Print: Anterior Versus Complete Corpus Callosotomy in Children

Background: Corpus callosotomy (CC) is a valuable palliative surgical option for children with medically refractory epilepsy due to generalized or multifocal cortical seizure onset.

Objective: To investigate the extent of CC resulting in optimal seizure control in a pediatric patient population and to evaluate the modification of seizure profile following various CC approaches.

Methods: The records of 58 children (aged 3-22 years at time of surgery) with medically refractory epilepsy who underwent CC between 1995 and 2011 were retrospectively reviewed.

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Written by NEUROSURGERY® Editorial Office

October 21, 2013 at 8:00 AM

Ahead of Print: Seizure Types After Temporal Lobectomy

Background: Temporal lobectomy can lead to favorable seizure outcomes in medically-refractory temporal lobe epilepsy (TLE). While most studies focus on seizure-freedom after temporal lobectomy, less is known about seizure semiology in patients who “fail” surgery. Morbidity differs between seizure types that impair or spare consciousness. Among TLE patients with seizures after surgery, how does temporal lobectomy influence seizure type and frequency?

Objective: To characterize seizure types and frequencies before and after temporal lobectomy for TLE, including consciousness-sparing or consciousness-impairing seizures.

Methods: We performed a retrospective longitudinal cohort study examining patients undergoing temporal lobectomy for epilepsy at our institution from January 1995 to August 2010.

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Written by NEUROSURGERY® Editorial Office

August 13, 2013 at 2:00 PM

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