Ahead of Print: Targeting the Pedunculopontine Nucleus

Background: Pedunculopontine Tegmental Nucleus (PPTg) deep brain stimulation (DBS) has been used in patients with Parkinson’s disease (PD).

Objective: To verify the position of the DBS lead within the pons during PPTg targeting.

Methods: In 10 PD patients undergoing electrode implantation in the PPTg, somatosensory evoked potentials (SEPs) were recorded after median nerve stimulation from the 4 DBS electrode contacts and from 2 scalp leads, placed in the frontal and parietal regions.