Posts Tagged ‘Recurrence’
Objective: Our study evaluated recurrence rates in patients with total endoscopic resection of colloid cysts versus those with coagulated cyst remnants.
Methods: Sixty-five consecutive patients and 67 procedures for endoscopic resection of colloid cysts from 1995 to 2011 were reviewed. Degree of resection was based upon intra-operative assessment and post-operative MRI. Recurrence rates were compared between patients with complete resection versus coagulated cyst remnants.
Background: Silent corticotrophic adenomas (SCAs) stain adrenocorticotropic hormone (ACTH)+ without causing Cushing’s disease. SCAs are reportedly more aggressive, but information comes from small series.
Objective: To determine whether SCAs behave more aggressively than Hormone-Negative Adenomas (HNAs), and characterize SCA ACTH production alterations.
Methods: SCAs (n=75) and HNAs (n=1726) diagnosed at our institution from 1990-2011 were retrospectively reviewed. RT-PCR was used to compare expression of ACTH-producing factors.
Background: Craniopharyngiomas (CRP) often cause visual deterioration (VD) due to the close vicinity of the optic apparatus.
Objective: To evaluate longitudinal visual outcomes after surgery of CRP and determine the prognostic factors thereof.
Methods: One hundred forty-six adult patients who underwent surgery for newly diagnosed CRP were retrospectively reviewed. There were 87 male patients (60%), and the median age was 41 years (range, 18 – 75). The mean follow-up duration was 88.7 months (range, 24 – 307). A visual impairment score (VIS) was used to assess the short-term (< 1 month) and long-term (> 2 years) visual outcomes.
Background: The natural history of surgically treated intracranial meningiomas can be quite variable. Recurrence and patient outcome cannot currently be predicted with accuracy.
Objective: To explore the potential roles of tumor hypoxia-regulated biological markers, preoperative imaging, measures of proliferation, and angiogenesis in predicting patient outcome.
Methods: Tissue from 263 patients (average follow-up, 75 months) was examined for molecular markers hypoxia-inducible factor-1α (HIF-1α), carbonic anhydrase-IX (CA-IX), and glucose transporter-1 (Glut-1); vascular endothelial growth factor (VEGF); proliferation (MIB-1); and microvascular density (MVD) (Factor VIII). Preoperative magnetic resonance images were also examined for tumor size and peritumoral brain edema (PTBE).
Objective: To elucidate the factors influencing tumor recurrence or progression and to determine how long these patient with cerebellar astrocytomas require surveillance with neuroimaging.
Methods: A retrospective review of 101 children surgically treated for a cerebellar astrocytoma and followed up for > 10 years was performed.