Ahead of Print: Endoscopic Transphenoidal Approach in Infants

Screen Shot 2014-11-06 at 9.26.39 AMBackground: Sella and suprasellar tumors are increasingly managed via an endoscopic transphenoidal approach, but infant endoscopic surgery has not been reported. Pituitary blastoma is a rare sellar malignant tumor that primarily occurs in infants, and is managed by surgical resection (cytoreduction) followed by adjuvant therapy.

Objective: To describe the technique and feasibility of resection of a pituitary blastoma via endonasal endoscopic transphenoidal approach in an 18-month infant.

Methods: Endoscopic endonasal transphenoidal approach for resection of a pituitary malignant tumor in an infant.

Results: Near-total tumor resection was achieved. The skull base was reconstructed using a nasoseptal flap with no CSF leak or any other intraoperative complications. The postoperative course was uneventful. One-year follow up showed complete resolution of the tumor.

Conclusion: Endoscopic endonasal transphenoidal approach with nasoseptal flap reconstruction could be used as a safe, yet, minimally invasive and innovative technique for the resection of pituitary blastoma in infants.

From: Endoscopic Transphenoidal Approach for Resection of Malignant Pituitary Blastoma in an 18-month-old Infant: A Technical Note by Zaben et al.

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