Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.
Seizures occurring in TSC are related to development of brain tumors, known as “tubers,” that develop in this disorder. But the new study by Dr. Aria Fallah of Miami Children’s Hospital and colleagues finds better outcomes when surgery includes the entire “epileptogenic zone” from which seizures are originating—not just the tuber itself.